Washington, DC locations
- Anacostia Neighborhood: Where Viola lives
- Arlington Methodist Hospital: Where Rob dies
- Armand's Pizzeria: Sofia likes to get lunch from here (original location was on Wisconsin Avenue)
- Bess Truman Park: Where Gabriel and Mischa meet
- Danbury Park: Where Arkady usually jogged, and Vlad is kidnapped
- Eastern Market: Stan and Nina’s safehouse was located near here
- Federal Bureau of Investigation (FBI) Headquarters, on Pennsylvania Avenue
- First Trinity Lutheran: Where Martha went to church
- Fort Lincoln Park: Elizabeth and Rennhull meet here in Season Six
- George Mason University: Where Oleg studies Urban Transport Planning
- Georgetown: Where Martha lives
- George Washington University: Todd, Hans and Paige were students here
- Huntley Meadows Park: Rennhull dies here
- The Jockey Club at the Fairfax Hotel: Kimmy’s dad takes her here for crab cakes on her birthday
- Kenilworth Neighborhood: Where Gregory lived
- The Key Theater: Where Elizabeth and Jackson watch Rififi
- Kingman Park: Where the pawnshop is located that tried to sell Amador’s ring
- Lincoln Memorial: Gabriel visits here at night and appears to be an admirer of Lincoln
- Marriott Marquis: Hotel where Bruce Dameran targets World Bank executives
- Naval Observatory: Where M. Hanley works
- Pentagon: Where Stan surreptitiously records the ECHO program
- Potomac Inn: Where Oleg stays when he returns to the US in Season Six
- Rock Creek Park: Where Martha went after fleeing from Gabriel
- Russian Embassy: Located on Wisconsin Avenue, site of the Rezidentura
- US Department of State: Elizabeth and McCleesh eat lunch at the employee cafeteria here
- Washington Hilton Hotel: Where Reagan was shot
- Woodley Park: Where Martha calls her parents
- World Bank Headquarters: Where Stan meets with Gary Lia about Bruce Dameran
Virginia Locations
- Alexandria: The Connors family is killed here, during the same time US scientists met with employees from Lockheed and Northrup
- Annandale: Where Clark and Martha get married
- Chesapeake: Where Fred’s house is located (and Philip is electrocuted)
- Crystal City: Where Elizabeth meets with a hotel manager and Abassin Zadran murders his colleagues
- Falls Church: Where the Jennings live
- Falls Church Commons: The name of the Jennings’ (fictional) neighborhood
- Franconia: Where an FBI janitor is recruited by the KGB to switch tapes from the mail robot
- Leesburg: Where Philip/Clark proposes to Martha
- Newington: Elizabeth breaks into a warehouse here, attempting to steal a sensor, and kills 3 employees
- Newport News: The Jennings steal propeller plans from the ship yards here
- Peterborough: Philip moves into a hotel here when he and Elizabeth separate
- Portsmouth: Calson Marine moves from Newport News to here
- Potomac River: Vasili stands looking at this, being watched by Stan, while Elizabeth murders Dorwin
- Quantico: Site of the FBI Academy
- Reston: The Jennings rent space at an office park here to meet with Andrew Larrick
- Virginia Beach: Where the Connors family lived. Elizabeth also meets with Mullin here.
Other US Locations, by State
Arizona
- Phoenix: Philip misidentifies this as the AZ capital when helping Henry study
- Tucson: Where one of Dennis’s sources ended up happily living
Arkansas
- Stan infiltrated white supremacists here
California
- Berkeley: Where Dennis went to University of California, to get his college degree at night
- Compton: Where Gregory wanted to move, instead of the USSR
- Oakland: Where Dennis grew up
- San Quentin: Stan says John Reisling is there now
- San Francisco: Dennis clerked in the FBI office here after high school
Colorado
Florida
- Bay Lake: EPCOT is located here
- Key West: Where Martha initially flew, when being exfiltrated
- Maurice goes to Florida (city unspecified) when he leaves Lisa
- Brian works for a US Congressman from an unspecified district in Florida
Georgia
Illinois
- Chicago: (The real) Elizabeth Korman was from here. There is an Altheon plant located here. Dan Murton ran an accounting business here, and the Jennings attempted to exfiltrate him from here, which results in Marilyn's death. The funeral for Stan’s FBI colleague was here.
- Naperville: Where Stan stayed when in town for his colleague’s funeral
- Skokie: Where Dan Murton lived
- Unspecified location: Elizabeth visits a greenhouse where experimental wheat is being grown
Indiana
- Notre Dame: Isaac Breland has a degree in theology from the University of Notre Dame
- West Lafayette: Bruce Dameran attended Purdue University here
Kansas
- Topeka: Roy Oatway graduated high school here. Elizabeth works Ben Stobert here. Philip works Deirdre here.
Kentucky
- (The real) William Crandall was born in Paducah and died in Bowling Green
- Philip suggests a Dude Ranch (city not specified) here, for Stan's colleague's bachelor weekend trip
Louisiana
Maryland
- Annapolis: Larrick taught at the US Naval War College here (although the actual location is Newport, RI)
- Baltimore: A weapons dealer and his daughter live here; Lewis Rendell lived here
- Port of Baltimore: Oleg leads Stan, Gaad and other FBI agents on a fruitless chase, ending here
- Bethesda: Site of Walter Reed Medical Center; Gaad and Dameran both spent time here
- Fort Detrick: The US bioweapons lab is located here. William and Hans both die here.
- Frederick: Where Ted Paaswell’s house is located
- Silver Spring: Elizabeth and Leanne conduct a mission here in 1966. The Morozov’s appear the live here as Holy Cross Hospital (where Pasha is taken) and the Quarry House Tavern (where Philip meets Alexei) are both located here.
- Kimberly and her friends unsuccessfully try to get admitted to a club here (unspecified city)
Massachusetts
- Boston: Travel agent Jerry lives here, as does one of Natalie’s daughters. Rob was based here, although because he had a wife and child in Philadelphia, he also lived there part time.
- Cambridge: Roy Oatway attended Massachusetts Institute of Technology here
- Newton: Natalie Granholm lives here
Michigan
- Kimmy went to college here, and Philip later visits her there. The Eckert family was supposedly from here.
Minnesota
- Minneapolis: (The real) Clark Westerfeld was from here. Game 6 of the 1987 baseball World Series was played at the Metrodome here, and watched at Martin Gurrin’s party.
Mississippi
- Where Philip and Elizabeth obtain a sample of Ben Stobert’s wheat (rural area, city unspecified)
Missouri
Nevada
- Reno: Bruce Dameran grew up here
New Hampshire
- Henry’s fictional school St Edward’s is located here
New York
New York City area locations:
- Carnegie Hotel: Philip meets Irina here and they frame Andrzej Bielawski
- Harlem: Where Jules Dassim grew up
- John F. Kennedy Airport: Where Mischa lands; where Gennadi allows the Soviet diplomatic pouch to be examined
- Statue of Liberty: The Jennings watch David Copperfield make it disappear on live tv
- Joyce moved here from Puerto Rico at the age of six, before moving to Philadelphia
Non-NYC locations:
- Rouse’s Point: where Paige gets off the train
- Upstate NY: Where Abigail’s cabin is located; where she, Larrick and Jared Connors die
North Dakota
Oklahoma
- Enid: Where Sofia and Gennadi were supposed to go into hiding
- Oklahoma City: The Jennings break into a lab and murder Randy Chilton here
Oregon
Pennsylvania
- Cresson: Where Aunt Helen lives
- Harrisburg: Where Tuan went to call his adoptive family in Seattle
- Philadelphia: Rob’s wife and son lived here
- Pittsburgh: Jared planned to attend Carnegie Mellon University here. Renee’s uncle has a scrap yard here. (The real) Philip Jennings was from here.
- Air force base, city not specified: Paige attends a protest here with Pastor Tim and Reed Street Church
- Tuscarora State Forest: The Jennings plan to take their children here as they make their way out of the country in the Season Two finale
Puerto Rico
- Where Joyce was born (city unspecified)
South Carolina
Tennessee
- Memphis: Gregory participated in a protest march here in the 1960s. The Jennings observe Ben meeting a woman here.
Texas
Washington
- Seattle: Where Tuan lived for 5 years with an adoptive family
West Virginia
- Jason’s dad (Henry’s friend) owns a tannery here (city unspecified)
Wyoming
- Casper: Where Brad Mullin grew up
- Cheyenne: One of the state capitals Philip and Henry study
Unspecific locations within the USA
- Blue Ridge Mountains: The Jennings took a camping trip here when their children were small
- Somewhere in the woods of Jefferson National Forest: Martial Eagle training camp located here
Non-USA Locations
USSR
- Crimea: Vacation spot where Oleg spent his summers.
- Dyatkovo: Where Natalie Granholm is from
- Gryazi: Elizabeth meets with Zhukov here in 1964, unhappy in her marriage to Philip
- Kasnsk: Where Yelena was imprisoned in the Kraslag labor camp
- Mikhaylovka: Where Nina is from
- Moscow: Where Oleg grew up, and attended Bauman Technical University. The Center and other government agencies are located here. Despite his negative attitude towards Russia, Alexei Morozov says Moscow was a nice place, only because of his mother.
- Odessa: Where Elizabeth dreams of living
- Sergach: Where Gabriel went, the first time he retired
- Sevsk: Where Natalie was born
- Smolensk: Where Elizabeth/Nadezhda grew up. She meets her mother at the Lopatinski Gardens there, to discuss her offer of becoming a Directorate S agent.
- Stalingrad: During the Battle of Stalingrad, Claudia’s youngest brother was killed and Elizabeth claims her father died fighting during the Battle of Stalingrad; Claudia met Zhukov shortly after the same battle.
- Tobolsk: A town in Western Siberia Where Philip/Mikhail grew up
- Vladivostok: Nina's letter about Anton's son was intercepted here
Afghanistan
- Faizabad: Mischa serves in the 345th Independent Paratroop Regiment here
- Ghazni: Mujahideen were killed by Lassa virus here
- Salang Pass: Site of a tunnel fire that killed a large number of Soviet troops
Argentina
- Buenos Ares: Where Pastor Tim moves
Australia
- Canberra: A lab that shipped the midges to Oklahoma is located here
- Philip postulates The Center may exfiltrate Jared to this country, since he'd be able to get by in English
Austria
Barbados
- Where Lacey honeymooned
Belgium
- Brussels: Where Evi’s boyfriend said to meet him, after she made the dead drop
Brazil
- Where Irina was captured
Bulgaria
Canada
- Ottowa: The Jennings plan to contact the Rezidentura here after they flee at the end of Season 2
- Montreal: Where Irina was based, where Elizabeth suggested Stan's colleagues should travel for a bachelor weekend
Costa Rica
Cuba
Czechoslovakia
- Where the pilot was from who transported bio-weapons obtained by William
Ecuador
- Where Pastor Tim went, after college
Egypt
- Ben Stobert lived here and learned to cook
El Salvador
- Where Father Rivas is from
Ethiopia
- Where Pastor Tim visits on a humanitarian mission, and gets lost
England/Great Brittain
- Oxford: Yousaf Rana attended college here
Eritrea
- Pastor Tim and a colleague decided to visit a village near this country’s border
Finland
- Sandra slept with a visiting university professor from here
France
- Where Betty's husband was stationed in World War II
- Andrjez Bielawski intends to establish a Polish government in Paris
Germany
- Where Anna fled during the war, and later met her husband
- (West): Where Elizabeth and Paige meet with Elizabeth’s mother; where the assassin is from that the Jennings try to stop
Greece
- Where Kimmy was going with college friends, over the Thanksgiving holiday
Hungary
- Elizabeth wonders if The Center may try to exfiltrate Jared here
Iceland
- Reykjavik: Where Nesterenko and Gorbachev worked together; where Reagan later met with Gorbachev
Israel
- Haifa: Where the Mossad agent is from
- Tel Aviv: Where Philip initially believes the Mossad agent is from
Italy
Jamaica
- Stan buys a vacation package to Jamaica from Philip, in an attempt to improve his marriage with Sandra
Japan
- Where Glenn Haskard was once posted, and he and his wife became Yakult Swallows fans. Where Philip tells Kimmy he’s moving, in the Season Five finale.
Kenya
- Nairobi: Where Charlotte was stationed and ran an operation for the CIA; where Tatiana was supposed to be transferred
- Pastor Tim pressures Philip to have his entire family join a mission trip here (city unspecified)
Korea
Mexico
- Mexico City: Elizabeth meets with General Kovtun here
The Netherlands
- Yousaf Rana was stationed here, and first assessed by the KGB as a potential informant
Nicaragua
- Where Lucia is from; where Larrick is transferred, site of the Nicaragua War
Pakistan
Poland
- Where Andrjez Bielawski is from
- Gdansk: Leanne's hometown
Prague
- Where Martha goes, after Cuba and before the USSR
South Africa
Sweden
Switzerland
- Zurich: Where Yousaf intends to get an apartment for Annelise
- Geneva: Elizabeth meets with Zhukov here in 1971, newly pregnant with Henry
- Elizabeth wonders if The Center may try to exfiltrate Jared here
Thailand
Vietnam
- Where Tuan is from. Frank Gaad, Chris Amador, Bruce Dameran and Andrew Larrick are among the characters who served here during the war.
Yugoslavia